Job Title: Research Scientist

A Research Scientist position in the smooth muscle Somlyo laboratory in the Department of Molecular Physiology and Biological Physics at the University of Virginia is immediately available. The NIH research focuses on the discovery of the contribution and the mechanism of action of our recently identified p90 ribosomal S6 kinase to the maintenance of basal tone, contractility and hypertension when activated by agonists and increased vascular intraluminal pressure. Outcomes will lay the groundwork for the future development of pharmaceuticals to treat smooth muscle based diseases and will also increase our basic understanding of smooth muscle contractility.

To apply, visit https://uva.wd1.myworkdayjobs.com/UVAJobs and search for R0007802 Research Scientist of Molecular Physiology and Biophysics. Please attach a cover letter, curriculum vitae, and contact information for three references to your application. Incomplete applications will not receive full consideration.

Duties include development of hypotheses, study design, performance of studies, data analysis and manuscript preparation. Experience with contractility measurements of isolated or permeabilized blood vessels from normal and transgenic mice following neurohumoral or mechanical stimuli or following the introduction of activatory or inhibitory peptides is essential; pressure myography of arteries; biochemical assays to identify signaling pathways including gel electrophoresis, western blotting, immuno-precipitation, Bio-Id, kinase assays; immuno-histochemistry and confocal microscopy; live cell imaging of Ca2+, pH in resistance vessels; molecular biology and cell culture skills including cell transfection of cells and blood vessels using adenoviral constructs to silence proteins of interest are preferred. Mouse husbandry.

MINIMUM REQUIREMENTS

Education: Ph.D. or terminal degree. ABD may be accepted.

Experience: None

Licensure: None

PHYSICAL DEMANDS

This is primarily a sedentary job involving extensive use of desktop computers. The job does occasionally require walking some distance to attend meetings, and programs.

The University of Virginia, including the UVA Health System and the University Physician's Group are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person's perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity, marital status, national or ethnic origin, political affiliation, race, religion, sex (including pregnancy), sexual orientation, veteran status, and family medical or genetic information.